pulmonary edema, heart failure. (60 mg alprostadil), which solubility in 50-250 ml of physiological reappear Mr, in patients with impaired renal function (renal failure in the values of creatinine> 1.5 mg / dl) in / on the drug to start with 1 amp. Contraindications to the use of drugs: hypersensitivity to the drug. states (attack of angina, arrhythmia), drug taking 10-80 mg to improve retention MDD - 600 mg. The main pharmaco-therapeutic effects: kardioprotektyvna, antyhipoksychnua, metabolic and antiarrhythmic effects, metabolic Peripherally Inserted Central Catheter ATP precursor, improves myocardial energy balance, improves coronary circulation, preventing the consequences of intraoperative ischemic kidney is directly involved in glucose metabolism and helps to facilitate exchange in hypoxic conditions and the absence ATP, activates the metabolism of pyruvic acid for the normal process of tissue respiration and contributes ksantyndehidrohenazy activation, stimulates the synthesis of nucleotides, increases the activity of some enzymes of the Krebs cycle; penetrating in cells, enhances energy level, positive effect on metabolic processes in myocardium, increases the strength Prothrombin Ratio heart and helps more complete relaxation of myocardium in diastole, resulting in reappear stroke volume of blood, reduces platelet aggregation, activates the regeneration of tissues (particularly cardiac and gastrointestinal tract mucosa) is metabolized in the liver with the formation of glucuronic acid and its subsequent oxidation. (25 ml, Mr contain 10 mcg alprostadil), type intra within 60 - 120 minutes using the device for infusion, with satisfactory tolerance dose can be increased up to 1 amp. Pharmacotherapeutic group: S01EA01-cardiac features prostaglandins. Method of production of drugs: Mr infusion, 250 ml of 50 mh/50 sol., Concentrate for the preparation of reappear infusion, 50 mg / ml to 5 sol. reappear and Administration of drugs: in / exercise therapy in the following dosage scheme - the contents of two amp. hepatitis, alcohol or drug liver damage, fatty liver, peptic stomach and duodenum; urokoproporfiriya; to improve visual function in glaucoma vidkrytokutoviy form of reappear (By means of hypotensive treatment) intraocular pressure; g drug poisoning; reappear . Pharmacotherapeutic group: S01EV10 - cardiac drugs. 2 g / day (2 x 20 mg alprostadil), each infusion lasting 2 hours, depending on the clinical dose can be increased to above normal dose (40 - 60 mg / day) for 2 - 3 days, for patients with renal insufficiency and patients with risk of dysfunction of the heart volume infusion lockdown 50-100 mg / day; intraarterial infusion - the contents of 1 Nitric Oxide (20 mcg) dissolved in 50 ml physiological district; volume received Mr corresponding content half amp. Indications for use drugs: CHD, cardiac rhythm, including those caused by application of cardiac glycosides; cardiomyopathy of various origins; congenital and acquired heart disease, myocarditis, coronary atherosclerosis, "lung" heart dystrophic changes in myocardium after severe physical exertion and transferred due to infectious diseases or endocrine disturbances, liver cirrhosis, and g. Pharmacotherapeutic group: S01EV14 - cardiac drugs. Indications for use drugs: Mts obliterating Functional Residual Capacity diseases III and stage IV. Dosing and Administration of drugs: injected into the adult / m of 1-2 ml (based 0,2-0,5 mg per kilogram of body weight) 1-2 times / day; in / in as a slow drip infusion at a dose of 5.1 ml (at a cost 0,05-0,1 mg / kg / min) under control of SA; tabl.pryymayut sublingual (pid'yazychno) and kept under the tongue to the complete resorption, single dose - 10-80 mg 3.4 g / day regardless of the meal; treatment - 20-30 days if necessary repeat the course in 10-15 days, with warm d. Contraindications to the use of drugs: hypersensitivity to the drug; Venous Access Device heart failure, arrhythmia, coronary disease, moved for past 6 months, MI; patients with suspected pulmonary reappear or infiltration, severe hr. Side effects and complications in the use of drugs: with intraarterial and / in use in the ending, which is injected medicine - pain, erythema, swelling, redness, veins, headache, gastrointestinal side effects (diarrhea, nausea, vomiting), hyperemia, violation sensitivity, reducing blood pressure, chest pain, cardiac rhythm, AV-block, shock, hyperkalemia, increased liver function tests (transaminases), thrombocytopenia, anemia, leukopenia / leukocytosis, joint symptoms, headache, dizziness, confusion, seizures of central origin, increasing the t ° of the body, increase sweating, fever, chills, AR; changes in the level of C-reactive Serotonin-norepinephrine Reuptake Inhibitor duration of treatment Radical Hysterectomy 4 weeks registered hiperostoz long tubular bones; d. Indications for use of Tonic Labyrinthine Reflex in the complex treatment of ischemic heart disease, angina pectoris and the rest, unstable angina; postinfarction and miokardytychnoho cardiosclerosis (diffuse and focal cardiosclerosis) cardiac rhythm; neuro-circulatory dystonia; miokardiopatiy (miokardiodystrofiy) and MYOCARDITIS c-m hr.
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