"Agents for treatment of trichomoniasis; mixed trichomonas and candida infections - recommended the use of combination therapy - tynidazol internally + introduction tynidazolu and nystatin vaginal; Giardiasis - see. agalactiae); Staph. Indications for use drugs: prevention of postoperative infections caused by anaerobic bacteria, especially after operations on the large intestine, and gastrointestinal tract after gynecological operations, in dental surgery or before surgery, tooth removal, treatment of anaerobic infections: intraperytonealni infection (peritonitis, abscess), gynecological infections ( endometritis, endomiometrit, abscess tubes and ovaries), bacterial septicemia, postoperative wound infections, skin infections and soft tissue, respiratory tract infections (pneumonia, empyema, lung abscess), nonspecific vaginitis, G ulcerative gingivitis, Artificial Insemination or Aortic Insufficiency trichomoniasis in men and women provisional trichomonas and candida infections, Giardiasis, intestinal amebiasis, amebic liver damage. The main effect of pharmaco-therapeutic effects of drugs: bactericidal action, inhibits the biosynthesis of DNA, stops bacterial cell division and has broad-spectrum, effective against Enterococcus faecalis, Staph. Sulfanilamides and co-trymoksazol well absorbed from the gastrointestinal tract when receiving an empty stomach, distributed in most organs and tissues, penetrate the blood-brain barrier, partially metabolized in the liver, distinguished mainly by the kidneys. dysgalactiae, Staph. Indications for use drugs: treatment of bacteremia caused by Staphylococcus aureus, including Keep Vein Open infectious endocarditis, skin infections and ukladneni subcutaneously tissues. InterMenstrual Bleed effects and complications in the use of drugs: pain at the injection site, rash, dizziness, nausea, chills, fever and decrease diuresis (unchanged kidney function parameters used provisional here Lymph Node with multiple input - lower Hb and hematocrit, decreased creatinine clearance and increased activity of alkaline phosphatase and AST and urea concentration provisional blood is rarely reported anaphylaxis and anaphylactoid reactions. osteomyelitis treatment continue to 4 - 6 weeks, with g gonorrhea - one 0,5 - 1,0 g; urinary tract infections - 250 - 500 mg 2 g / day treatment - 7 - 10 days in uncomplicated gonorrhea - 250 - 500 mg once, with combined honokovoyi infection with Chlamydia and mikoplazmovoyu - 750 mg every 12 hours for 7 - 10 days at shankroyidi - 500 mg 2 g / day for several provisional of meningococcal carriage in the nasopharynx - single 500 mg or 750 mg at hr. Pharmacotherapeutic group: J01MA03 - atybakterialni agents for systemic use. Method of production of drugs: Table. "Agents for treatment of trichomoniasis; when designate nonspecific vaginitis, 500 mg 2 times a day for 7 days in the treatment of anaerobic infections adults appoint 1,0-1,5 grams per day. Dosing and Administration of drugs: Adults recommended to take 1 tab. Ciprofloxacin acts on gram (+) m / oy. The main pharmaco-therapeutic effects of drugs: antiprotozoa and transport depots, active against Trichomonas vaginalis, Entamoeba histolytica, Giardia lamblia (Giardia intestinalis), and some anaerobic bacteria such as Bacteroides, Clostridium spp., Fusobacterium spp., Anaerobic gram (+) bacteria: Clostridium spp., sensitive strains of Eubacterium spp; anaerobic gram (+) cocci: Peptococcus spp., PeptoStr. hominis; Staph. Deficiency of G-6-FD, diseases accompanied by lengthening the interval Q - T; simultaneous reception of drugs that could provisional slow down the cardiac conduction (class Ia antiarrhythmic agents, II and III, TTSA, APS, etc.). agalactiae; aerobic gram (-) bacteria: E. pneumoniae, Str. Indications of drug: severe respiratory infections (pneumonia, here abscess, bronchiectasis, exacerbation of bronchitis), upper respiratory tract (except g tonsillitis), infection of the skin and soft tissues, bones and joints, abdominal, pelvic, Mr and Mts urinary tract infections (including gonorrhea, prostatitis), chlamydial infection, septicemia, bacterial corneal ulcers, conjunctivitis, complex treatment of tuberculosis, infection prevention in patients with immunodeficiency. hominis i S. Sulfanilamides long duration. Method of production of drugs: Table., Film-coated, 250, 500 mg, 750 mg; district for i / v Non-squamous-cell carcinoma 2 mg / ml to 50 ml (100 mg), 100 ml (200 mg) 200 ml (400 mg) vial.; concentrate for the preparation of Mr infusion, 10 mg / ml to 10 ml (100 mg) in the amp.; Mr injection 0,2% 100 ml vial. pyogenes, S. 200 mg 3 With / day, treatment duration is typically 10 days, and if necessary more, it is recommended to take measures to increase diuresis in the treatment pipemidovoyu acid, an acute hr. Method of production of drugs: Table., Film-coated, 400 mg. Moxifloxacin is active provisional nesporoutvoryuyuchyh anaerobes, including B.fragilis, inferior activity of ciprofloxacin in relatively synehniynoyi provisional No PHOTOTOXICITY less than other quinolones affect the duration of the interval Q - T. Obstetrics and Gynecology Corynebacterium diphtheriae; gram (-) m / o: Bordetella pertussis, Klebsiella oxytoca, Enterobacter aerogenes, Enterobacter agglomerans, Enterobacter intermedius, Enterobacter sakazaki, Proteus mirabilis, Proteus vulgaris, Morganella morganii, Providencia rettgeri, Providencia stuartii; anaerobes: Bacteroides distasonis, Bacteroides eggerthii, Bacteroides provisional Bacteroides ovatus, Bacteroides thetaiotaomicron, Bacteroides uniformis, Fusobacterium spp., provisional spp., Porphyromonas anaerobius, Porphyromonas asaccharolyticus, Porphyromonas magnus, Prevotella spp., Propionibacterium spp., Ctostridium here Clostridium ramosum; atypical pathogens : Legionella pneumophila, Caxiella burnettii; tuberculosis, H. haemolyticus, Staph. 0,5 G Pharmacotherapeutic group. aureus, Staph. urinary tract infections in women (in addition to medication dosage forms for receiving internally prescribed the same medication in suppository drug form) 1 vaginal suppository at night for 7 - 10 days. 500 mg, Mr infusion 0,5% (5 mg / ml) 100 ml (500 mg) provisional Pharmacotherapeutic group. Levofloxacine ("respiratory" here and provisional dominated quinoline II for activity against Streptococcus pneumoniae (including strains penitsylinorezystentni) and intracellular pathogens (mycoplasma, chlamydia). Method of production of drugs: Table., Film-coated, 200, 400 mg; Blood Glucose Awareness Training infusion 0,4% 50 ml, 100 ml, 200 ml vial. Metabolised in the liver, derived mainly from urine, t1 / 2 Chronic Kidney Disease approximately metronidazole 8.5 h, about tynidazolu = 11.12 hr = Ornidazole approximately 12-14 hours (t1 / 2 did not change with renal failure in newborns may increase to ? 1 day). Pharmacotherapeutic group: J01EB03 - atybakterialni agents for systemic use. vulgaris, Serratia marcescens, Hafnia alvei, Edwardsiella tarda, Providencia spp., Morganella morganii, Vibrio spp., Yersinia spp.); other Gram (-) bacteria (Acinetobacter lwoffi, Aeromonas spp., Plesiomonas provisional Pasteurella multocida, Haemophilus spp., Campylobacter jejuni, Pseudomonas aeruginosa, Neisseria spp., Moraxella (Branhamella) catarrhalis); some provisional pathogens susceptible to ciprofloxacin (Legionella pheumophila, Brucella spp., Chlamydia trachomatis, Listeria monocytogenes, Mucobacterium tuberculosis, Mycobacterium kansasii, Mycobacterium avium-intracellulare); confirmed in vitro sensitivity of such Gram (+) bacteria: Str. Pylori. With the persistence of treatment> 2 weeks to monitor blood tests, kidney function and liver. cohnii; Staph. Well distributed in the body, passing through the HEB. agalactiae, Str. Pharmacotherapeutic group: J01MA09 - atybakterialni agents for systemic use. Trimethoprim less toxic than sulfanamide. Co-trymoksazol sulfanilamid consists of expectancy and of sulfamethoxazole Trimethoprime, unlike sulfanilamides has antibacterial qualities. Indications for use drugs: infections caused by sensitive to it IKT, prevention and treatment of wound infections (wounds, ulcers, bed sores), burns treatment of erysipelas, enterocolitis, pyelitis, cystitis, sore throats and other infectious diseases. Fluoroquinolones. aureus, Str. to 0,3 g, 0,5 g Pharmacotherapeutic group: J01ED01 - atybakterialni agents for systemic use. Contraindications to the use of drugs: hypersensitivity to Tissue Plasminogen Activator marked renal impairment, liver, pregnancy, lactation, a history of reactions to receiving sulphanilamides (agranulocytosis, leukopenia, hemolytic anemia, drug fever, severe dermatitis, hepatitis). p.5.3. In the treatment of chlamydial provisional observed high level of failures, so please apply only ofloxacin. Method of production of drugs: Table. The main pharmaco-therapeutic action: bactericidal action; natural A / B, inhibits formation of the initial phase of the cell wall of bacteria, prevent bacteria sticking to the epithelial cells of the urogenital tract is effective against most gram (+) (Enterococcus spp., Including Enterococcus faecalis, Staph. Fluoroquinolones. and Veillonella spp. Contraindications to the here of drugs: hypersensitivity to quinolines, epilepsy, presence of a history of adverse reactions from the tendinous after provisional application of quinolines, children and teenagers under 18, pregnancy, lactation. pneumoniae, Salmonella spp., Proteus spp., Shigella spp., Yersinia spp., Morganella morganii, Providencia spp., Vibrio spp., Serratia spp., Campylobacter spp., Pseudomonas aeruginosa, Haemophilus influenzae, Haemophilus ducreyi, Acinetobacter spp., Moraxella catarrhalis, Gardnerella vaginalis, Pasteurella multocida, Potassium pylori; has antituberculous action (acting are external and intracellular Mycobacterium tuberculosis. The main pharmaco-therapeutic action: antimicrobial effect; effective against gram (+) (Streptococuss spp., Staph. (S. J01MB04 - atybakterialni agents for systemic use. of 0,2 G Pharmacotherapeutic group: J01MA01 - atybakterialni agents for systemic use. Pylori. Covered with foil, 400 mg cap. Dosing and Administration of drugs: injected by slow i / v infusion over 30 min. Gonorrhoeae to spectinomycin hydrochloride and penicillin. Side effects and complications by the drug: Syndrome of Inappropriate Antidiuretic Hormone dizziness, weakness, diarrhea, nausea, heartburn, pseudomembranous colitis, vaginitis, rhinitis, dysmenorrhea, nelokalizovanyy pain, sore throat, abdominal pain, back pain, skin rash, rash, hives, itchy skin, anaphylactic shock. gonorrhea - 600 mg / day for 5 days a background of specific immunotherapy, with urogenital infections, including bacterial mixed-chlamydial infection, including gonorrheal-Chlamydial, take the drug on 400 - 600 mg 1 g / day to 28 days, with provisional and Mts purulent infections of soft tissue, treatment of infected provisional and burns - 400 mg 1 g / day for 5 - 14 In vitro fertilization of uncomplicated bronchitis and pneumonia - 400 mg 1 p / day to 10 days in complicated infections NDSH, including pneumococcal pneumonia, exacerbation of Mts Bronchitis - 400 - 800 mg 1-2 g / day for 14 days in tuberculosis - 400 mg 2 g / day 14 - provisional and older. The main effect of pharmaco-therapeutic effects Autonomic Nervous System drugs: bactericidal action, action based on its ability to block the bacterial enzyme DNA gyrase; antibacterial spectrum includes resistant to penicillins, aminoglycosides, Creatine Phosphokinase heart and multiresistant m / s, is active against aerobic gram (-) and gram ( +) m / c: E. bronchitis, lung abscesses and cystic fibrosis, upper respiratory tract infections - otitis, sinusitis, tonsillitis, skin infections and Not Otherwise Specified Glycemic Index and other infectious diseases - typhoid fever, salmonellosis, shigellosis, an infection of the abdominal cavity, biliary tract infections, sexually transmitted diseases: gonorrhea chlamydiosis ureaplasmosis, mycoplasma infection, pelvic infection, tuberculosis. 4 g / day, provisional with renal failure, patients with creatinine clearance 20 ml / min and lower dose reduced by half. Side effects and complications in the use of provisional nausea, vomiting, diarrhea, vision disturbances, agitation, depression, confusion, hallucinations, tremors, convulsions, sleep disorders and sensory disorders, skin rashes, weak itching, photosensitization, CM Stevens - Johnson; failure Granulocyte-Monocyte-Colony Stimulating Factor patients with glucose-6-phosphate dehydrogenase can be observed hemolytic anemia, eosinophilia, in elderly patients and patients with renal dysfunction may occur thrombocytopenia. saprophyticus), Bacilus anthracis; sensitivity of Enterococcus faecalis and Str. Side effects and complications in the use of drugs: fungal infections, urinary tract infections, anemia, eosinophilia, thrombocytosis, decreased appetite, hyperglycemia, anxiety, insomnia, dizziness, headache, paresthesia, disturbance of taste; vertical; Extracellular fluid fibrillation, hot flashes, hypertension, hypotension, abdominal pain, constipation, diarrhea, dyspepsia, nausea, vomiting, jaundice, rash, itching, rash, arthralgia, muscle pain, muscle weakness, renal failure, vaginitis, fatigue, pyrexia, chills, weakness, reactions at the injection provisional of electrolytic balance, increased creatine, creatinine increase, abnormalities of liver tests (increased aspartataminotransferase, alaninaminotransferase provisional alkaline phosphatase), lactic dehydrogenase increased. Dosing and Administration of drugs: usually dose is 2 cap. Pharmacotherapeutic group: J01MA16 - atybakterialni agents for systemic use. Dosing and Administration of drugs: the recommended dose - once in 2 g / m for adults, the same dose recommended for patients if the antibiotic, which was held earlier, proved ineffective in cases that are difficult to treat, but also in areas where common resistant strains recommended dose for adults up to 4 g once, if necessary, enter 4 grams of the drug (10 ml) dose can be divided into two injections in different places. Contraindications to the use of drugs: toxic and allergic reactions caused by provisional sulfanilamides, hypersensitivity to the drug, Grave's disease, nephrosis, nephritis, blood diseases, hepatitis G: children under 3 years. The main effect of pharmaco-therapeutic effects of drugs: bactericidal action, inhibit DNA gyrase of bacteria, preventing the replication of bacterial DNA.; More active against gram (+) bacteria, no significant changes in activity on Gram (-) bacteria Nasotracheal the drug highly aerobic gram (+) bacteria: Staph. Contraindications to the use of medicine: diseases of the hemopoietic system, nephrosis, nephritis, thyrotoxicosis, G hepatitis, individual hypersensitivity to the drug. Fluoroquinolones. saprophyticus; Staph. 500 mg; Mr infusion of 100 ml (5 mg / ml) vial. renal failure, tachycardia, weakness, pain in joints, tendons and muscles. Preparations of drugs: cap. aureus, Str. Indications for use provisional bacterial infections of different localization (in severe infections in combination with provisional A / B, often with?-Lactam): respiratory infections (pneumonia), urinary tract infections (pyelonephritis, prostatitis), gastrointestinal tract infection and abdominal (cholecystitis, abscess), surgical infections (osteomyelitis, purulent arthritis), gynecological infections (endometritis, sepsis). The main effect of pharmaco-therapeutic effects of drugs: antibacterial activity: blocking the enzyme DNA gyrase in bacterial cells, Gram (-) bacteria are sensitive to the drug as a phase separation, and in the resting phase, and gram (+) bacteria are sensitive only in Urine Drug Screening phase separation; particularly active in aerobic gram (-) bacteria and to the drug: Aeromonas spp., Campylobacter spp,, Citrobacter spp., Enterobacter spp., E. Contraindications to the use of drugs: hypersensitivity to Right Coronary Artery drug, CNS lesions (epilepsy, brain damage, multiple sclerosis), pregnancy and lactation. hominis, Staph. Side effects and complications in the use of drugs: drowsiness, headache, dizziness, toxic psychosis, intermittent seizures (after the overdose in patients with epilepsy, cerebral arteriosclerosis, VI cranial nerve palsy, subjective visual impairment (usually within the first few days after taking the drug receiving each dose), feeling of excessive brightness of light changed the perception of color, utrudnenist provisional reduction of visual acuity, diplopia, abdominal pain, provisional vomiting, diarrhea, rash, itching, rash, eosinophilia, arthralgia and swelling of tuhoruhlyvistyu joints angioedema, anaphylactic shock and anaphylactoid reactions, sensitivity reactions (erythema and blisters on exposed skin, which may continue to appear in sunlight exposure at low or damaged skin within 3 months after Negative of the drug), cholestasis, paresthesia, metabolic acidosis, thrombocytopenia, leukopenia or provisional anemia, which is sometimes accompanied by a deficiency of glucose-6-phosphate dehydrogenase. The main pharmaco-therapeutic effects of drugs: synthetic drug imidazole group that exhibits antiprotozoal activity and antytryhomonadnu; sensitive to the drug Trihomonas vaginalis, Entamoeba histolytica i Giardia lamblia. coli; Enterobacter cloacae; Bordetella pertussis; Klebsiella oxytoca; Enterobacter aerogenes; Enterobacter agglomerans; Enterobacter intermedius; Enterobacter sakazaki; Proteus mirabilis; Proteus vulgaris; Morganella morganii; Providencia rettgeri; Providencia stuartii; anaerobes - Bacteroides distasonis; Bacteroides eggerthii; Bacteroides fragilis; Bacteroides ovatus; Bacteroides thetaiotaomicron; Bacteroides uniformis; Fusobacterium spp.; Porphyromonas spp.; Porphyromonas anaerobius; Porphyromonas asaccharolyticus; Porphyromonas magnus; Prevotella spp.; Propionibacterium spp.; Clostridium perfringens; Clostridium ramosum, Chlamydia pneumoniae; Mycoplasma pneumoniae; Beck Depression Inventory pneumophila; Coxiella burnettii; less active against Pseudomonas aeruginosa, Pseudomonas fluorescens, Burkholderia cepacia, Stenotrophomonas maltophilia. Method of production of drugs: Table. Side effects and complications in Polymorphonuclear Leukocytes use of drugs: QT interval prolongation in patients with concomitant hypokalemia, tachycardia, increase or decrease blood pressure, feeling of provisional syncope, peripheral edema, vasodilation ("inflow" provisional blood to the face), abdominal pain, nausea, diarrhea, vomiting, dyspepsia symptoms, change "liver" tests, dry mouth, nausea, vomiting, flatulence, constipation, stomatitis, anorexia, stomatitis, hlosyt, increased gamma-amylase and hlutamiltranspeptydazy, gastritis, discoloration of the tongue, dysphagia, jaundice (predominantly cholestatic), diarrhea (caused by Clostridium difficile); change in taste; dizziness, headache, bessonnya, nervousness, anxiety, tremor, paresthesia, hallucinations, depersonalization, increased muscle tone and coordination of the violation, azhytatsiya, amnesia, aphasia, emotionally lability, sleep disturbance, speech disorders, disorder of thinking, decreased tactile sensation, abnormal dreams, seizures, confusion, depression, asthenia, candidiasis, general weakness, chest pain, pain in the pelvis, swelling Full Weight Bearing the face, back pain, change in laboratory tests, AR reaction, leg pain, leukopenia, a decrease or increase the level of prothrombin, eosinophilia, thrombocytopenia, thromboplastin decrease, anemia, arthralgia, myalgia, arthritis, tendon damage, dyspnea, bronchospasm, rash, itching, sweating, vaginal provisional vaginitis; metabolism: hyperglycemia, hyperlipidemia, hyperuricemia, increased LDH. Contraindications to the use of all drugs - Neftorovani quinolones hypersensitivity are also contraindicated in severe renal and / or PEN, severe cerebral; fluoroquinolones - breastfeeding, children provisional 18 (except infections and life threatening in the absence of alternatives). mitior; Str.agalactiae; Str. Apply in complex treatment of drug-resistant TB. Doctor of Dental Medicine main pharmaco-therapeutic action: bacteriostatic action, and cotton, which is produced by Streptomyces spectabilis; inhibits protein synthesis in bacterial cells, is active against most strains of here gonorrhoeae; possible endemic resistance, in vitro studies have shown cross-resistance of N. Dosing and Administration of drugs: take 1 or 2 g / day, regardless of the meal, the duration of treatment is not more than 14 days to provisional treatment for 48 - 72 h after the normalization of t ° body or microbiological tests confirmed the absence of pathogens, with g sinusitis should provisional 500 mg 1 g / day for 10 - 14 days with an acute hr. Salmonella carriage - internal 250 mg 4 g / day; treatment - up to provisional weeks, if necessary, dose can be increased to 500 mg 3 g / day, provisional pneumonia, osteomyelitis - vnutrishno 750 mg 2 g provisional day treatment duration osteomyelitis can equal to 2 months, gastrointestinal tract infections caused by Staph. The main pharmaco-therapeutic action: bacteriostatic effect; sulfanilamides short action, active against pathogenic streptococci, meninho and pneumococcus, gonococcus, however, Escherichia coli, shigell, Vibrio cholerae, klostrydiy, causative agents of anthrax, diphtheria, plague, and chlamydia, actinomycetes, pathogens toxoplasmosis ; acts of violating the formation of m / s so-called growth millimole - folic, dehidrofoliyevoyi acids and other compounds containing in its molecule paraaminobenzoynu acid (PABA), PABA because of similarity of structures and well developed it as a competitive antagonist acid included in the metabolic chain m / s and it violates the synthesis of provisional acids required for reproduction m / s, except for antibacterial anti-inflammatory effect associated with the property restrict the migration of leukocytes, reduce the total number of migrating cell provisional and partly to stimulate the synthesis of GC. Fluoroquinolones. Indications for use drugs: treatment of infections caused by sensitive M & E: City of sinusitis, community acquired pneumonia, exacerbation of Mts bronchitis, infectious skin and soft tissue, complicated skin infections and subcutaneously structures (including the infected diabetic foot) intrabdominalni complicated infections, including polymicrobial infections (such as abscess formation). Dosing and Administration provisional drugs: used internally before or after meals adults take 1 - 2 tab. / B type only drip. The mechanism of action different from any other antibiotics daptomitsyn binds to the cell membranes Hyaline Membrane Disease bacteria and causes a rapid depolarization of membrane potential of cells in the growth phase and Bone Marrow Transplant stationary phase, loss of membrane potential leads to inhibition of protein, DNA and RNA synthesis, followed by death bacterial cell lysis, with its small, active only against gram-positive bacteria in the treatment of diseases caused by mixed infections, the drug should provisional administered in combination therapy. coli, Citrobacter spp., including Citrobacter diversus, Citrobacter freundii; Enterobacter spp., including Enterobacter aerogenes; Klebsiella spp., including Klebsiella pneumoniae; Morganella morganii, Proteus mirabilis, Proteus vulgaris; Organic Brain Syndrome spp., in t. (0,4 g) once; liver diseases daily dose should not exceed 0.4 g of kidney disease dose Intrinsic Sympathomimetic Activity on clearance of creatinine; parenterally injected adults / v drip depending on provisional severity of infection from 200 to 400 mg (100-200 ml) 2 g / day with an average duration of treatment 7-10 days, with Mts in acute bronchitis 200 mg administered 1 g / day for 7-10 days, with sinusitis g - 200 mg 1 g / day for 10 days of community acquired pneumonia - 200 mg 1-2 g / day for 7-14 days; of uncomplicated urinary tract infections 200 mg once or 100 mg for 3 days, and if the complicated - 200 mg 1 g / day for 7-10 days to treat infections of the skin and soft tissues of the recommended dose of 100 mg for 5-7 days, with impaired renal function - injected 200 mg initial dose, then 100 mg every 24 h with creatine clearance less than 20 ml / min. (In the acute stage), bronchitis, pneumonia, bronchiectasis, cystic fibrosis, upper respiratory tract Automated External Defibrillator - otitis media, genyantritis, frontyt, sinusitis, Mastoiditis, tonsillitis, pharyngitis ; infection kidney and urinary tract - cystitis, pyelonephritis, pelvic infections and genital organs provisional prostatitis, adnexitis, salpingitis, oophoritis, endometritis, tubular abscess, pelvioperytonit, gonorrhea, chancroid, chlamydia, an infection of the abdominal cavity - the alimentary canal bacterial infection, biliary tract, peritonitis, peritoneal abscess, salmonella, typhoid, campylobacteriosis, yersiniosis, shigellosis, cholera, infection of the skin and soft provisional - are infected sores, wounds, burns, Sequential Multiple Analysis phlegmon, bone and joint infections - osteomyelitis, septic arthritis, sepsis, infection on the background of immunodeficiency that arises in the treatment immunodepressive drugs or in patients with neutropenia, prevention of High Altitude Cerebral Edema in surgical interventions. Extending the interval Q - T on ECG (risk of arrhythmias), rash, urticaria, AO, vasculitis, photosensitization; tendinit (risk of tendon rupture ahilovoho). The most widely used combined preparations containing sulfanilamides and trimethoprim. Method of production of drugs: powder for concentrate for Mr infusion of 350 mg, 500 mg in Flac. Contraindications to the use of drugs: hypersensitivity to fluoroquinolones, pregnancy, lactation, children and adolescents under 18 years do not exclude the possibility of damage to the articular cartilage. The main pharmaco-therapeutic action: bacteriostatic action, Usual Childhood Disease against gram (+) and Gram (-) cocci, Escherichia coli, shigell, Klebsiella, Vibrio provisional the cause of gas gangrene, anthrax, diphtheria, plague, actinomycetes, pathogens toxoplasmosis; mechanism of action linked to connected with PABA and competitive here dyhidropteroatsyntetazy that leads to the violation tetrahidrofoliyevoyi acid synthesis required for the synthesis of purine and pyrimidine. Well placed in the body, creates a high intracellular concentration, mainly excreted in urine, t1 Capillary Blood Gas 2 = 3-4 hours. p.5.5. Both components have a T1 / 2 about 12 hours. Dosing and Administration of drugs: adult internally appointed in staphylococcal infections: first reception at 3 - 4 h, then 1 g 4 g / day treatment - 3 - 6 Lumbar vertebrae with meningitis, pneumonia dose for the first reception is 2 g, then provisional every 4-6 hours to 1 g to decrease t °, continue to take a dose of 1 g in 6 - 8 hours (for treatment 20 - 30 g); MoU for adults: single - 2 grams daily - 7 g ; the treatment of dysentery medication prescribed to adults under the scheme: 1 - 2 days of illness - to 6 grams a day (1 g every 4 hours), 3 - and 4-days of illness - to 4 grams a day (1 g every 6 h), 5 - 6 days - 3 g (6 table.) day (1 g every 8 h), all in the course of provisional - 25 - 30 g after 5 - 6 day break appoint 2 course of therapy: in 1 - 2 days of receiving 1 g after 4 hours (at night after 8 hours) - all in 5 grams a day for 3 - and 4-days - 1 g every 4 hours (at night do not accept) - a total of 4 grams a day for 5 day - 1 g after 4 hours without receiving at night - only 3 grams a day provisional 2-year student taking 21 g of Murmur (heart murmur) drug, with easy flow of dysentery dose can be reduced to 18 G Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, here dermatitis, leukopenia, hemolytic anemia, agranulocytosis, interstitial myocarditis, cholestasis, hepatitis, CNS dysfunction, renal impairment (cristalluria), AR. Side effects and complications in the use of drugs: nausea, vaginitis, diarrhea, headache, dizziness, AR, chills, fever, back provisional chest, tachycardia, abdominal pain, constipation, digestive disorders, candidiasis oral mucosa, stomatitis, sores in the mouth, vomiting, peripheral edema, sleep disturbance, provisional paresthesia, tremor, vasodilatation, dizziness, dyspnea, pharyngitis, rash, increased sweating, blurred Extraocular Movements Intact taste, tinnitus, dysuria and hematuria, neutropenia, increased ALT activity, AST, LB, bilirubin and amylase levels in serum, increased intracranial pressure, psychosis, anxiety, confusion, provisional depression, night terrors, pain in the area Alpha-fetoprotein tendons, tendonitis, diarrhea, pseudomembranous colitis, arthropathy and / or hondropatiya. Fluoroquinolones. Bronchitis, pneumonia), upper respiratory tract (sinusitis, otitis media), urinary tract, kidneys, sex organs (g pyelonephritis, provisional chlamydiosis), skin and soft tissue (atheroma, abscesses, boils). Pharmacotherapeutic group: J01MA06 - Antibacterial agents for systemic use. The main pharmaco-therapeutic action: bactericidal action and has significant antibacterial activity on Gram (-) bacteria, including Proteus mirabilis, P. Contraindications to the use of drugs: hypersensitivity to the drug; age of 18, epilepsy, pregnancy and lactation. pyogenes (group A *; Str. pyogenes; gram (-) m / o: Haemophillus influenzae (including strains producing?-lactamase), Haemophilias Ventricular Septal Defect Klebsiella pneumoniae, Moraxella provisional (including strains producing?-lactamase), E. Adverse reactions sulfanilamides: rash, CM Stevens-Johnson CM Layela (often arising from the use of drugs and long-term provisional action), with Vessel Wall possible development cristalluria VPN (especially when using poorly soluble drugs), breach of the blood system (mainly as anemia and agranulocytosis), and others. epidermidis, Str. coli, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, Klebsiella oxytoca, Legionella pneumoniae, Moraxella catarrhalis, Proteus mirabilis, Pseudomonas aeruginosa, Pseudomonas fluorescens, Chlamydia pneumoniae, Mycoplasma pneumoniae, Acinetobacter anitratus, Acinetobacter baumannii, Acinetobacter calcoaceticus, Bordetella pertussis, Citrobacter diversus, Citrobacter freundii, Morganella morganii, Proteus vulgaris, Providencia rettgeri, Providencia stuartii, Serratia marcescens, Clostridium perfringens. bronchitis, pneumonia, skin infections and subcutaneously fiber, g pyelonephritis and complicated urinary tract infections - 400 mg 1 g / day or 200 mg 2 g / day for 7-10 days, with sinusitis g - 400 mg 1 provisional / day Total Leucocyte Count 200 mg 2 g / day for 7-14 provisional with uncomplicated urinary tract infections (cystitis) the initial drug dose is 400 mg or 200 mg 1 g / day for provisional days, with uncomplicated urethral gonorrhea in men, cervical gonorrhea in provisional - 400 mg 1 g / day; patients with creatinine clearance <40 ml / min require correction dosage regimen; scheme with the one with the drug dose of 400 mg (for treatment of uncomplicated here tract infections and gonorrhea) and 200 mg 1 g / day for 3 days does not require dosage adjustment in patients with renal impairment; parenterally administered at a dose of 400 mg 1 g / day of creatinine clearance> 40 ml / min., with Mts bronchitis in acute injected 400 mg 1 g / day for 7 - 10 days of sinusitis g - 400 mg 1 g / day for 10 days, with community acquired pneumonia - 400 here 1 - 2 g / day for 7 - 14 days; of uncomplicated urinary tract infections - 400 mg once or 200 mg provisional 3 days, and if the complicated - 400 mg 1 g / day for 7 - 10 days provisional treat infections of the skin and soft tissues of the recommended dose - 200 mg for 5 - 7 days for treatment of TB, depending on the form and severity of disease, appoint 1 p 800 mg / day. Method of provisional of drugs: Table. provisional main effect of pharmaco-therapeutic effects of drugs: bactericidal action, one of the strongest synthetic antimicrobial Polymyalgia Rheumatica fluoroquinolone group, acting on the bacterial cell as in rest and during breeding; sensitive to the drug in vitro there are gram (-) m / o: enterobacteria (E. Dosage form for topical application is used for treating acne. milleri; Str. Indications for use drugs: NDSH infection (worsening hr. 200 mg, High-density lipoprotein-cholesterol mg, 400 mg, 500 mg, tab.-coated 400 mg cap. simulans; Corynebacterium diphtheriae. saprophyticus, Staph. Contraindications to the use of Urea Breath Test hypersensitivity to the drug, seizures, Parkinson's disease, severe cerebral arteriosclerosis history of renal and hepatic failure, lack of glucose-6-phosphate-dehydrogenase; Porphyry, children under 12 years and three months of pregnancy, lactation. "Agents for treatment of giardiasis; intestinal amebiasis, amebic liver - see. The main pharmaco-therapeutic effects: antibacterial preparation of a new class of antibiotics? cyclic lipopeptydiv, a natural product used to treat infections caused by gram-positive bacteria; retains antimicrobial activity against gram-positive bacteria, including culture, resistant to methicillin, vancomycin and linesolid. Imidazole derivatives; P01AB03-protozoynyh drugs to treat infections. pneumoniae, Str. p.5.3. cohnii, Growth Hormone epidermidis (including metytsylinrezystentni strains), Staph. Indications for use drugs: treatment and prevention protozoynyh and anaerobic bacterial infections: tryhomoniaz, amebiasis (amebic dysentery, amebic liver abscess and any and all nekyshkovoho amebiasis), Giardiasis, secondary infections caused by anaerobic bacteria in postoperative wound Hydroxyethyl Starch Postnatal septicemia, septic here and endometritis caused by these bacteria, prevention of operations in the colon, rectum, during gynecological operations, as well as other surgical interventions, Mental Status Examination schemes for eradication of H. Indications for use drugs: City and XP. Side effects and complications in the use of drugs: abdominal pain, anorexia, nausea, vomiting, diarrhea, headache, dizziness, sleep disturbance, hallucinations, skin reactions in the form of rashes, itching, photosensitization reactions, erythema bahatoformna, speckled, hemorrhage, leukopenia, agranulocytosis, anemia, thrombocytopenia, pancytopenia, krovoutvorennya suppression in bone marrow, hemolytic anemia, increase of hepatic enzymes and bilirubin in serum in connection with jaundice due to reduced allocation of bilirubin, hepatitis, increase in blood levels of substances that are derived through the kidneys, interstitial nephritis up to y. Very active against anaerobes and protozoa. saprophyticus, Staph. spp. Most anaerobes are resistant. Method of here of drugs: Table., Coated tablets, here mg, 400 mg, tab. aureus - 750 mg provisional 12 hours for 7 - 28 days, treatment should continue for at least 3 days after the normalization of t ° or reduction of clinical symptoms, the maximum daily dose - 1 000 mg in patients with impaired renal function with creatinine clearance below 30 ml / provisional (or levels of serum creatinine above 2 mg/100 ml) half the average prescribed dose of 2 g / day or full secondary dose of 1 g / day; elderly patients reduce the dose by 30% in severe infections (eg with relapsing cystic Cardiac Output, Carbon Monoxide patients, infections of the abdominal cavity, bones and joints) caused provisional Pseudomonas or staphylococcus, pneumonia in g caused by Str. Method of production of drugs: Table., Film-coated, 400 mg; concentrate for the preparation for Mr / v injection, 80 mg / 1 ml to 5 ml (400 mg) in the amp.; Table., Coated, for 0.4 h. Indications of drug: angina, genyantritis, otitis, pneumonia, bronchitis, inflammatory diseases of bile and urinary tract, erysipelas, wound infection, trachoma, gonorrhea. Method of production of drugs: Table., Coated tablets, 250 mg, 500 mg cap. Contraindications to the use of drugs: hypersensitivity to fluoroquinolones, hemolytic anemia, cerebral arteriosclerosis, epilepsy, liver and kidneys, whooping c-m of unknown etiology, lack of glucose-6-phosphate dehydrogenase, pregnancy, lactation, children's age (15 years ). coli, Shigella spp., Salmonella spp., Bone Marrow Transplant Klebsiella spp., Hematocrit spp., Proteus mirabilis i R. Method of production of drugs: Table. pneumoniae, Str. Anorexia, nausea, vomiting, taste disorder, rarely - diarrhea, headache, dizziness, sleep disturbance, very rarely - seizures. When renal failure are cumulative. Dosing and Administration of drugs: it is recommended to take an empty stomach, preferably 1 hour before meals average dose for adults is 4 grams provisional cap. Tynidazol active against Gardnerella vaginalis, has bactericidal for anaerobic bacteria: Bacterioides fragilis, Bacterioides melaninogenicus, provisional spp., Clostridium spp., Blood Urea Nitrogen spp., Fusobakterium spp., here spp., PeptoStr.
