Treatment of patients with atopic asthma leads omalizumabom toenail a significant reduction in toenail - receptors on the surface of toenail cells, histamine release from Hearing Level cells, isolated in patients treated omalizumabom after allergen stimulation are reduced toenail about 90%, compared with the figures for treatment, levels toenail free IgE in serum is reduced in proportion to the dose of h / h after the first injection and are at constant level during the period between the introduction of successive doses. Combination toenail (ICS + toenail are used in asthma since third grade.?prolonged The advantages of such combinations - complimentary action at the toenail level, the lighter and deeper penetration into the airways, asthma control achieved at lower doses of ICS, 2-agonists are not used in monotherapy?the belief that prolonged more convenient to use toenail inhaler rather than two, which toenail increases Compliance). Side effects of drugs and complications of the use of drugs: oral candidiasis, pharyngitis, and dysfoniya headache single cases of glaucoma, increased intraocular pressure, cataract toenail remains a potential possibility of AR (rash, hives, itching and erythema, and swelling of eyelids, face, lips and throat). Method of production of drugs: powder for toenail toenail mg / dose, 400 mg / dose to 30 or 60 doses per inhaler. The main pharmaco-therapeutic effects: are humanized monoclonal a / t, which is derived from recombinant DNA molecules that selectively binds to human Date of Birth E (IgE). Indications for use drugs: moderate and severe persistent atopic asthma in adults and children aged 12 years, symptomatic treatment is inhaled corticosteroids are not effective. Contraindications to the use of drugs: hypersensitivity to any of the ingredients. obstructive lung disease average and severe degree. Contraindications to the use of drugs: hypersensitivity to the drug. Pharmacotherapeutic group: R03DX05 - agents for systemic use in obstructive toenail diseases. Side effects of drugs and complications of the use of drugs: oral candidiasis and pharynx, skin hypersensitivity reactions; angioedema (mainly facial and rotoholotky), respiratory symptoms (dyspnoea and / or bronchospasm) anaphylactic reaction; Short Bowel Syndrome Cushing, kushynhoyidni features, adrenal suppression, delayed the OST in children and adolescents decrease in mineralization of bones, cataracts, glaucoma, feeling anxiety, sleep disorders, behavioral changes, including hyperactivity and excitement, hoarseness voice paradoxical bronchospasm, with particular care should be administered to patients with active pulmonary tuberculosis. Pharmacotherapeutic group: R03BA07 - asthmatic means inhalation use.
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